CYP19A1 polyclonal antibody
产品名称： CYP19A1 polyclonal antibody
英文名称： CYP19A1 polyclonal antibody
产品编号： PAB12453
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CYP19A1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 400-502 of human CYP19A1.
- Host:
- Rabbit
- Reactivity:
- Bovine, Horse, Human, Primates, Rabbit
- Specificity:
- This antibody is specific to aromatase.
- Form:
- Liquid
- Storage Buffer:
- In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Dynamic changes in gene expression that occur during the period of spontaneous functional regression in the rhesus macaque corpus luteum.
Bogan RL, Murphy MJ, Hennebold JD.Endocrinology. 2009 Mar;150(3):1521-9. Epub 2008 Oct 23.
- 2.
- Systematic determination of differential gene expression in the primate corpus luteum during the luteal phase of the menstrual cycle.
Bogan RL, Murphy MJ, Stouffer RL, Hennebold JD.Mol Endocrinol. 2008 May;22(5):1260-73. Epub 2008 Feb 7.
- 3.
- Aromatase-immunoreactivity is localised specifically in neurones in the developing mouse hypothalamus and cortex.
Beyer C, Green SJ, Barker PJ, Huskisson NS, Hutchison JB.Brain Res. 1994 Feb 28;638(1-2):203-10.
- Entrez GeneID:
- 1588
- Protein Accession#:
- P11511
- Gene Name:
- CYP19A1
- Gene Alias:
- ARO,ARO1,CPV1,CYAR,CYP19,MGC104309,P-450AROM
- Gene Description:
- cytochrome P450, family 19, subfamily A, polypeptide 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq
- Other Designations:
- OTTHUMP00000162543,aromatase,cytochrome P450, family 19,cytochrome P450, subfamily XIX (aromatization of androgens),estrogen synthetase,flavoprotein-linked monooxygenase,microsomal monooxygenase
- Gene Pathway
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Adenocarcinoma
- Adenocarcinoma, Bronchiolo-Alveolar
- Adenocarcinoma, Mucinous
- Alopecia
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Juvenile Rheumatoid
- Arthritis, Rheumatoid
- Asperger Syndrome
- Atherosclerosis
- Autistic Disorder
- Breast cancer
- Breast Neoplasms
- Cadaver
- Carcinoma
- Carcinoma, Ductal, Breast
- Carcinoma, Hepatocellular