AKR1C2 polyclonal antibody (A01)
产品名称： AKR1C2 polyclonal antibody (A01)
英文名称： AKR1C2 polyclonal antibody (A01)
产品编号： H00001646-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant AKR1C2.
- Immunogen:
- AKR1C2 (AAH63574, 224 a.a. ~ 323 a.a) partial recombinant protein with GST tag.
- Sequence:
- EEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPVSDEY
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis.
Su JG, Liao PJ, Huang MC, Chu WC, Lin SC, Chang YJ.Toxicology. 2008 Feb 28;244(2-3):257-70. Epub 2007 Dec 7.
- 2.
- Molecular Functional analysis of the Tumor Suppressor Gene PDCD4.
Marikkannu R.FB 12 Chemie und Pharmazie
- Applications
- Western Blot (Cell lysate)
- AKR1C2 polyclonal antibody (A01), Lot # CIL0060112QCS1 Western Blot analysis of AKR1C2 expression in HeLa ( Cat # L013V1 ).
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of AKR1C2 expression in transfected 293T cell line by AKR1C2 polyclonal antibody (A01).
Lane1:AKR1C2 transfected lysate(37 KDa).
Lane2:Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Entrez GeneID:
- 1646
- GeneBank Accession#:
- BC063574
- Protein Accession#:
- AAH63574
- Gene Name:
- AKR1C2
- Gene Alias:
- AKR1C-pseudo,BABP,DD,DD2,DDH2,HAKRD,HBAB,MCDR2
- Gene Description:
- aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
- Omim ID:
- 600450
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
- Other Designations:
- OTTHUMP00000018995,OTTHUMP00000044759,aldo-keto reductase family 1, member C2,chlordecone reductase homolog,pseudo-chlordecone reductase,trans-1,2-dihydrobenzene-1,2-diol dehydrogenase,type II dihydrodiol dehydrogenase
- Gene Pathway