Anti-ACTN1 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002308P-50ul	solarbio	50ul	960.00元
K002308P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-ACTN1 Polyclonal Antibody
别名	BDPLT15
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Monkey
蛋白分子量	103kDa
Gene ID	87
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human ACTN1
性状	液体
Public Immunogen Range	Recombinant protein of human ACTN1
Subcellular Locations	Cell junction Cell membrane Cell projection Cytoplasm Z line cytoskeleton myofibril ruffle sarcomere
Swiss Prot	P12814
克隆类型	Polyclonal Antibody
背景资料	Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.