HSPA5 polyclonal antibody
产品名称： HSPA5 polyclonal antibody
英文名称： HSPA5 polyclonal antibody
产品编号： PAB12413
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HSPA5.
- Immunogen:
- A synthetic peptide corresponding to amino acids 250-300 of human HSPA5.
- Host:
- Rabbit
- Reactivity:
- Bovine, Chicken, Fruit fly, Human, Mouse, Nematoda, Primates, Rat, Sheep, Zebra fish
- Form:
- Liquid
- Storage Buffer:
- In PBS (30% glycerol, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention.
Chiu CC, Lin CY, Lee LY, Chen YJ, Kuo TF, Chang JT, Liao CT, Wang HM, Yen TC, Shen CR, Liao SK, Cheng AJ.Mol Cancer Ther. 2008 Sep;7(9):2788-97.
- Entrez GeneID:
- 3309
- Protein Accession#:
- P11021
- Gene Name:
- HSPA5
- Gene Alias:
- BIP,FLJ26106,GRP78,MIF2
- Gene Description:
- heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
- Omim ID:
- 138120
- Gene Ontology:
- Hyperlink
- Gene Summary:
- When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM
- Other Designations:
- Heat-shock 70kD protein-5 (glucose-regulated protein, 78kD),OTTHUMP00000022124,heat shock 70kD protein 5 (glucose-regulated protein, 78kD),heat shock 70kDa protein 5
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Bipolar Disorder
- Carcinoma, Hepatocellular
- Cognition
- Disease Susceptibility
- Genetic Predisposition to Disease
- Hepatitis B
- Hepatitis B, Chronic
- Infection
- Kidney Failure, Chronic
- Liver Neoplasms
- Parkinson Disease
- Parkinson disease
- Schizophrenia
- Schizophrenia
- Stress, Psychological