AK1 polyclonal antibody
产品名称： AK1 polyclonal antibody
英文名称： AK1 polyclonal antibody
产品编号： PAB4039
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of AK1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human AK1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Red cell adenylate kinase deficiency: molecular study of 3 new mutations (118G>A, 190G>A, and GAC deletion) associated with hereditary nonspherocytic hemolytic anemia.
Corrons JL, Garcia E, Tusell JJ, Varughese KI, West C, Beutler E.Blood. 2003 Jul 1;102(1):353-6. Epub 2003 Mar 20.
- 2.
- Congenital haemolytic anaemia associated with adenylate kinase deficiency.
Toren A, Brok-Simoni F, Ben-Bassat I, Holtzman F, Mandel M, Neumann Y, Ramot B, Rechavi G, Kende G.Br J Haematol. 1994 Jun;87(2):376-80.
- 3.
- Regional assignment of the loci for adenylate kinase to 9q32 and for alpha 1-acid glycoprotein to 9q31-q32. A locus for Goltz syndrome in region 9q32-qter?
Zuffardi O, Caiulo A, Maraschio P, Tupler R, Bianchi E, Amisano P, Beluffi G, Moratti R, Liguri G.Hum Genet. 1989 Apr;82(1):17-9.
- Entrez GeneID:
- 203
- Protein Accession#:
- NP_000467;P00568
- Gene Name:
- AK1
- Gene Alias:
- -
- Gene Description:
- adenylate kinase 1
- Omim ID:
- 103000
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq
- Other Designations:
- ATP-AMP transphosphorylase,OTTHUMP00000022217,OTTHUMP00000022218,myokinase
- Gene Pathway
- Related Disease