F3 monoclonal antibody (M01), clone 4G4
产品名称： F3 monoclonal antibody (M01), clone 4G4
英文名称： F3 monoclonal antibody (M01), clone 4G4
产品编号： H00002152-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant F3.
- Immunogen:
- F3 (AAH11029, 45 a.a. ~ 154 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- TWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTK
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- F3 monoclonal antibody (M01), clone 4G4 Western Blot analysis of F3 expression in A-431 ( Cat # L015V1 ).
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of F3 expression in transfected 293T cell line by F3 monoclonal antibody (M01), clone 4G4.
Lane 1: F3 transfected lysate(33.1 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunoprecipitation
- Immunoprecipitation of F3 transfected lysate using anti-F3 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with F3 MaxPab rabbit polyclonal antibody.
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged F3 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- In situ Proximity Ligation Assay (Cell)
- Proximity Ligation Analysis of protein-protein interactions between F7 and F3. HeLa cells were stained with anti-F7 rabbit purified polyclonal 1:1200 and anti-F3 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
- Entrez GeneID:
- 2152
- GeneBank Accession#:
- BC011029
- Protein Accession#:
- AAH11029
- Gene Name:
- F3
- Gene Alias:
- CD142,TF,TFA
- Gene Description:
- coagulation factor III (thromboplastin, tissue factor)
- Omim ID:
- 134390
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000012426,coagulation factor III,tissue factor
- Interactome
- Gene Pathway
- Related Disease
- Acute Disease
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Cardiovascular Diseases
- Carotid Stenosis
- Chorioamnionitis
- Coronary Thrombosis
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Edema
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Hemorrhage
- Kidney Failure, Chronic
- Metabolic Syndrome X
- Myocardial Ischemia