MAP2K4 polyclonal antibody
产品名称： MAP2K4 polyclonal antibody
英文名称： MAP2K4 polyclonal antibody
产品编号： PAB5570
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAP2K4.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding S80 of human MAP2K4.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation.
Park HS, Kim MS, Huh SH, Park J, Chung J, Kang SS, Choi EJ.J Biol Chem. 2002 Jan 25;277(4):2573-8. Epub 2001 Nov 13.
- Entrez GeneID:
- 6416
- Gene Name:
- MAP2K4
- Gene Alias:
- JNKK,JNKK1,MAPKK4,MEK4,MKK4,PRKMK4,SEK1,SERK1
- Gene Description:
- mitogen-activated protein kinase kinase 4
- Omim ID:
- 601335
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. [provided by RefSeq
- Other Designations:
- JNK activating kinase 1,JNK-activated kinase 1,MAP kinase kinase 4,MAPK/ERK kinase 4,SAPK/ERK kinase 1,c-Jun N-terminal kinase kinase 1,dual specificity mitogen-activated protein kinase kinase 4