DDB1 (Human) Recombinant Protein (Q01)
产品名称: DDB1 (Human) Recombinant Protein (Q01)
英文名称: DDB1 (Human) Recombinant Protein (Q01)
产品编号: H00001642-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human DDB1 partial ORF ( NP_001914, 1044 a.a. - 1140 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- SESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH
- Theoretical MW (kDa):
- 36.41
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 1642
- GeneBank Accession#:
- NM_001923
- Protein Accession#:
- NP_001914
- Gene Name:
- DDB1
- Gene Alias:
- DDBA,UV-DDB1,XAP1,XPCE,XPE,XPE-BF
- Gene Description:
- damage-specific DNA binding protein 1, 127kDa
- Omim ID:
- 600045
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq
- Other Designations:
- DDB p127 subunit,damage-specific DNA binding protein 1,damage-specific DNA binding protein 1 (127kD)